CONFIDENCE INTERVAL FOR THE DIFFERENCE BETWEEN TWO POPULATION MEANS
EXERCISES
For each of the following exercises construct 90,95, and 99 percent confidence intervals for the difference between population means. Where appropriate, state the assumptions that make your method valid. State the practical and probabilistic interpretations of each interval that you construct. Consider the variables under consideration in each exercise, and state what use you think researchers might make of your results.
6.4.1: The objective of an experiment was to study effect of pancuronium-induced muscle relaxation on circulating plasma volume. Subjects were newborn infants weighing more than 1700 grams who required respiratory assistance within 24 hours of birth and met other clinical criteria. Five infants paralyzed with pancuronium and seven nonparalyzed infants yielded the following statistics on the second of three measurements of plasma volume (ml) made during mechanical ventilation:
Subject group Sample mean Sample standard deviation
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Paralyzed 48.0 8.1
Nonparalyzed 56.7 8.1
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The second measurement for the paralyzed group occurred 12 to 24 hours after the first dose of pancuronium. For the nonparaslyzed group. Measurements were made 12 to 24 hours after commencing mechanical ventilation.
ANSWER
(a) 0.1035 , 17.2964
(b) 8.1324, 29.2676
(c) -6.3316, 23.7316