IUGR

I. U .G.R.
I.U.G.R. is a major cause of neonatal
morbidity & mortality.
Certain adult diseases including
hypertension & diabetes are related to
I.U.G.R.
I.U.G.R. Is defined as failure of the fetus to
acheive its genetic growth potential .
S.G.A.: fetus or neonate is below a certain
defined centile of weight or size for a
particular gestational age ( below 3rd or 5th
centile ) ,and SGA are constitutionally small
due to normal genetic influences.
While IUGR indicates that a particular

pathological process is operating to modify
the intrinsic growth potential of the fetus by
1-Reduced fetal growth potential
(intrinsic)
inadequate trophoblast invasion ( e.g HT,
PET ),
Antiphospholipid syn. ,D.M with vascular
lesions advanced ), sickle cell disease ,
multiple pregnancy .
Antepartum complications
1- stillbirth (fetal death in IUGR more
frequent after 35 weeks of
gestation ) .
2- oligohydramnios ( in severe IUGR due
to vasoconstriction in the fetal kidney
results in impaired urine production ).
3- Antepartum fetal distress.
A-chromosome defect e.g trisomy 18 ,
triploidy.
B-single gene defects e.g seckel’s synd.
C-structional abn. e.g renal agenesis
D-infection e.g TORCH
reducing its growth rate .