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Titration

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الكلية كلية الطب     القسم الكيمياء الحياتية     المرحلة 1
أستاذ المادة بان محمود شاكر الجودة       07/02/2017 22:21:05
Titration
Titration, also known as titrimetry , is a common laboratory method of quantitative chemical analysis that is used to determine the unknown concentration of an identified analyte. Since volume measurements play a key role in titration, it is also known as volumetric analysis. A reagent, called the titrant is prepared as a standard solution . A known concentration and volume of titrant reacts with a solution of analyte or titrand to determine concentration. The volume of titrant reacted is called titration volume.

Types of titrations
1-Acid–base titration .
2-Redox titration.
3-Gas phase titration .
4-Complex metric titration.
5-Zeta potential titration.
Acid–base titration
Acid-base titrations depend on the neutralization between an acid and a base when mixed in solution. In addition to the sample, an appropriate pH indicator is added to the titration chamber, reflecting the pH range of the equivalence point. The acid-base indicator indicates the endpoint of the titration by changing color. The endpoint and the equivalence point are not exactly the same because the equivalence point is determined by the stoichiometry of the reaction while the endpoint is just the color change from the indicator. Thus, a careful selection of the indicator will reduce the indicator error . For example, if the equivalence point is at a pH of 8.4, then the Phenolphthalein indicator would be used instead of Alizarin Yellow because phenolphthalein would reduce the indicator error. Common indicators, their colors, and the pH range in which they change color are given in the table above .When more precise results are required, or when the reagents are a weak acid and a weak base, a pH meter or a conductance meter are used.


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