White Blood Cells

White Blood Cells

Neutrophilic Polynuclear cells neutrop.jpg - 4.5 K 1-
circulating WBC. diameter 12um 60—70% a-
Lobed nucleus, 2-5 shape variable, drumstick [heterochromatin b-
Granules c-
purple with Wrights stain, [staining varies among mammals 1-
[0.3-0.8um] size limit of light microscope 2-
Formed by Golgi 3-
azurophilic, 1st promyelocyte, lysosomal enzymes & peroxidase 4-
5- neutrophilic, 1st myelocyte, alkaline phospahtase, bacterialcidal substances, Phagocytins
Acute infection, highly mobile, highly phagocytic d-
Spherical in the blood, amebiform [forms pseudopodia]on solid substrate
e- both types of granules fuse with phagosome, granules decrease in number after phagocytosis
Functions in anerobic enviroment of necrotic tissue f-
Terminal cell, once it uses its proteins, can not be replaced g-
Myeloid element h-

Eosinophilic Polnuclear cells eosinophil.jpg - 3.8 K 2-
1% - 4% circulating WBC. diameter 9um a-
Bilobed nucleus b-
Granules, c-
Ovoid 1-
Red with Wrights stain, Eosinophilic 2-
Larger than neutrophils 3-
No lysosome, acid phospahtase, ribonuclease, cathepsin 4-
5- Elongated crystalloid [phospholipids & unsaturated fatty acids] surrounded by unit membrane
Not highly mobile or phagocytic d-
Phagocytosis of Selective Antigen antibody complexes e-
Increses in number in allergic reactions and parasitic infections f-
Myeloid element g-

Basophilic Polynuclear cells 3-
0% - 1% circulating WBC. diameter 12um a-
Large twisted s shaped nucleus b-
Granules, c-
Irregular in size and shape 1-
Blue/metachromatic staining Basophilic 2-
Larger than other granuocytes 3-
Histamine & Heparin 4-
Released in the presence of certain antigens 5-
Surrounded by unit membrane 6-
Not very active or phagocytic d-
Myeloid element e-

Large lymphocytes, small lymphocytes 4-

circulating WBC. diameter 6-8um 25 – 40 % a-
Heterogenous population of cells, small, medium, & large b-