Abstract:
The study was carried out in Al-Hashimyia hospital, Babylon governorate for the period from May, 2005 to May ,2006 to evaluate the results of some immunological tests in diagnosis of acute phase of brucellosis in human populations. A total of 410 patients with suspected brucellosis were admitted to the hospital with age-group ranged from 18 to 65 years. 150 patients were studied, as documented cases with acute brucellosis , and 150 healthy persons were involved as control group. Numerous immunological tests like ELISA test , Rose- Bengal test , standard tube agglutination test and E-rosette test were used to demonstrate cellular and humoral immune response of infected host . ELISA test was the best and accurate test in diagnosis of the acute infection, followed by standard tube agglutination test . All cases of acute brucellosis showed a high number of active rosette –forming cells.

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Key words: Human brucellosis , Acute infection, Immunological tests.