Synthesis and spectroscopic studies of some Schiff bases
derived from Benzidine and their conversion to 1, 3-oxazepine derivatives throughout
[2+5] cycloaddition reactions (II) .

Abstract:

The present work is oriented towards synthesis of some new series of 1,3-oxazepine derivatives through out two pathways .The first one is reaction of Benzidine with different substituted aldehyde such as ( p- hydroxyl , p-methoxy, o -bromo benzaldehyde and vaniline ) throughout condensation reaction under refluxing condition in presence of absolute ethanol, acidic to produced imines derivatives (w5-w8) .The second one is reactions of the prepared imines (w5-w8) with maleic and phthalic anhydride under inert N2 gas and refluxing conditions to produces a new series of 1,3- oxazepine derivatives (w5m –w8m) and (w5ph-w8ph) respectively . All the preparing compounds well monitored and identified by TLC and spectroscopic tools such as IR,1H-NMR and Elemental analysis.